Wrist Pain Prevention/Pain Management

Like many of you, I've got wrist pains. I've tried everything. Better chair, modified desk for correct height, ergonomic mouse/keyboard. Only thing helps the pain to go away is taking a vacation. What are you guys doing to prevent wrist pain or manage it? I'm trying wrist braces now but amazon has all these fake reviews, I'm not even sure if I got a good brace or not.